3.5.3 Pharmacology I
Lab 5 Effect of Atrophine on Rabbit's or Guineapig's eyes
Developed by Prova Biswas
Aim of practical: Purpose of this experiment is to evaluate the pharmacological action of Atropine Sulphate (1% w/v) on eye diameter, light reflex and corneal reflex of Rabbit.
Theory: Atropine, a belladonna alkaloid, has a high affinity for muscarinic receptors, where it competitively prevents acetylcholine from binding to the sites. It is a non selective blocker of muscarinic receptors. Atropine has the opposite actions to Pilocarpine, on the Rabbit's eye.
[Tortora G. J., Principals of
Anatomy and Physiology, Twelfth Edition, Willey publishers, 2009]
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