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B.Pharm Lab. Instruction Manuals

Pharmacology I

APHE Anatomy, Physiology, and Health Education

Pharmaceutical Analysis

Pharmacy study material

Bones and Skeleton System

Bone disease (Gout) (Rheumatoid arthritis) (Osteoarthritis) (Osteoporosis)

Cancer and music therapy

Memory of water

Dosage and monitoring tests for anti-rheumatoid drugs

Abatacept (Orencia)

Common mechanism of action

Inhibits T cell activation and promotes it's down regulation by inhibiting APC.

Major adverse drug reactions (ADRs)

Risk of infection if used with anti TNF drugs.

Monitoring test

None.

Doses

30-minute IV weight-based infusion: 60 kg = 500 mg; 60-100 kg = 750 mg; >100 kg = 1,000 mg.

Auranofin

Common mechanism of action

Auranofin affects polymorphonuclear cells (PMNC) and monocytes at lower concentrations and affects humoral and cell-mediated immunity; it also have inhibitory effect on IL-1.

Major adverse drug reactions (ADRs)

Systemic lupus erythematosus (SLE), congestive heart failure, renal dysfunction, blood dyscrasias.

Monitoring test

Baseline: urine analysis (UA), CBC with platelets and then every 1-2 months.

Doses

Oral: 3 mg once or twice daily.

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