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B.Pharm Lab. Instruction Manuals

Pharmacology I

APHE Anatomy, Physiology, and Health Education

Pharmaceutical Analysis

Pharmacy study material

Bones and Skeleton System

Bone disease (Gout) (Rheumatoid arthritis) (Osteoarthritis) (Osteoporosis)

Cancer and music therapy

Memory of water

Dosage and monitoring tests for anti-rheumatoid drugs

Cyclosporine

Common mechanism of action

Immunosuppressant, inhibit the IL-2 and it's receptor followed by the suppression of T cell proliferation.

Major adverse drug reactions (ADRs)

Nephrotoxicity, hypertension.

Monitoring test

Scr, blood pressure every month.

Doses

Oral: 2.5 mg/kg/day.

Corticosteroids

eg. Oral: Prednisolon, Methylprednisolone, Intramascular (IM) or Intraarticular injections: Triamcinolone acetonide, Triamcinolone hexacetonide, Methylprednisolone acetate.

Common mechanism of action

Act by inhibiting macrophages and cytokines, anti-inflammatory action by inhibiting the migration of PMNC and reversal of increased capillary permeability, suppression of the immune system by reducing the activity and production of the lymphocytes and eosinophils.

Major adverse drug reactions (ADRs)

Immunocompromization, osteoporosis following increased osteoclast activity, glaucoma, homeostasis imbalance, Cushing's syndrome, growth retardation in children, hyperglycaemia, and hypertension, poor wound healing.

Monitoring test

Glucose; blood pressure every 3-6 months.

Doses

Oral, IV, IM, IA, and soft-tissue injections: variable.

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