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B.Pharm Lab. Instruction Manuals

Pharmacology I

APHE Anatomy, Physiology, and Health Education

Pharmaceutical Analysis

Pharmacy study material

Bones and Skeleton System

Bone disease (Gout) (Rheumatoid arthritis) (Osteoarthritis) (Osteoporosis)

Cancer and music therapy

Memory of water

Dosage and monitoring tests for anti-rheumatoid drugs

NSAIDs

Common mechanism of action

Act by inhibiting cyclooxygenase (COX) enzyme thus relief from the signs and symptoms of inflammation (redness, swelling, pain).

Major adverse drug reactions (ADRs) of NSAIDs

Gastro intestinal tract intolerance, gi ulcer, nephrotoxicity.

Monitoring test for NSAIDs

Serum creatinine (Scr) or blood urea nitrogen (BUN), complete blood count (CBC) every 2-4 weeks after starting therapy for 1-2 months; salicylates: serum salicylate levels if no response in therapeutic dose, guaiac every 6-12 months.

Aspirin

Doses: Adults: 2.6-5.2 g; children: 60-100 mg/kg; four times daily.

Celecoxib

Doses: Adults: 200-400 mg once or twice daily.

Diclofenac

Doses: Adults: 150-200 mg three to four times daily; extended release: twice daily.

Diflunisal

Adults: 0.5-1.5 g twice daily.

Etodolac

Adults: 0.2-1.2 g (max, 20 mg/kg); two to four times daily.

Tolmetin

Adults: 0.6-1.8 g ; children: 15-30 mg/kg ; two to four times daily.

Sulindac

Adults: 300-400 mg twice daily.

Piroxicam

Adults: 10-20 mg once daily.

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