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B.Pharm Lab. Instruction Manuals

Pharmacology I

APHE Anatomy, Physiology, and Health Education

Pharmaceutical Analysis

Pharmacy study material

Bones and Skeleton System

Bone disease (Gout) (Rheumatoid arthritis) (Osteoarthritis) (Osteoporosis)

Cancer and music therapy

Memory of water

Dosage and monitoring tests for anti-rheumatoid drugs

NSAIDs

Common mechanism of action

Act by inhibiting cyclooxygenase (COX) enzyme thus relief from the signs and symptoms of inflammation (redness, swelling, pain).

Major adverse drug reactions (ADRs) of NSAIDs

Gastro intestinal tract intolerance, gi ulcer, nephrotoxicity.

Monitoring test for NSAIDs

Serum creatinine (Scr) or blood urea nitrogen (BUN), complete blood count (CBC) every 2-4 weeks after starting therapy for 1-2 months; salicylates: serum salicylate levels if no response in therapeutic dose, guaiac every 6-12 months.

Oxaprozin

Doses: Adults: 0.6-1.8 g (max, 26 mg/kg); one to three times daily.

Nonacetylated salicylates

Doses: Adults: 0.5-1 g 10 mg/kg twice daily; extended release: once daily.

Naproxen

Doses: Adults: 150-200 mg three to four times daily; extended release: twice daily.

Naproxen sodium

Adults: Adults: 0.55-1.1 g twice daily.

Meclofenamate

Adults: Adults: 200-400 mg three to four times daily.

Meloxicam

Adults: 1-2 g once or twice daily.

Nabumetone

Adults: 300-400 mg twice daily.

Ibuprofen

Adults: 1.2-3.2 g ; children: 20-40 mg/kg; three to four times daily.

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