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B.Pharm Lab. Instruction Manuals

Pharmacology I

APHE Anatomy, Physiology, and Health Education

Pharmaceutical Analysis

Pharmacy study material

Bones and Skeleton System

Bone disease (Gout) (Rheumatoid arthritis) (Osteoarthritis) (Osteoporosis)

Cancer and music therapy

Memory of water

Dosage and monitoring tests for anti-rheumatoid drugs

MTX

Common mechanism of action

Inhibits cytokine production and purine biosynthesis and thus stop the progression of inflammation.

Major adverse drug reactions (ADRs)

Pulmonary fibrosis.

Monitoring test for MTX

Baseline: aspartate aminotransferase (AST or SGOT), Alanine transaminase (SGPT or ALT), Alkaline phosphatase (ALP), albumin, total bilirubin, hepatitis B and C studies, CBC with platelets, Scr followed by CBC with platelets, AST, albumin every 1-2 months.

Doses

Oral or IM: 7.5-15 mg/wk .

Leflunomide

Common mechanism of action

Acts by inhibiting the activated T cells.

Major adverse drug reactions (ADRs)

Elevated liver enzymes, alopecia, diarrhoea.

Monitoring test

Baseline: ALT, CBC with platelets CBC with platelets and ALT monthly initially, and then every 6-8 weeks

Doses

Oral: 100 mg daily for 3 days, then 10-20 mg daily; or 10-20 mg daily without loading dose.

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